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Picks for the 2008 Regular Season, Week 16
The Line numbers are relative to the home teams. A negative number indicates the visiting team is favored.
The upset picks for this week are Baltimore, Carolina and San Diego.
| Home | Opening | Visitor | Our Picks | By | Money | O/U |
| line | | | | Line | |
| | | | | | |
| Jacksonville | -7 | Indianapolis | Indianapolis | 9 | -260 | 44 |
| Dallas | 5 | Baltimore | Baltimore | 2 | +180 | 41 |
| Cleveland | 3 | Cincinnati | Cleveland | 8 | -135 | 39 |
| Denver | 7 | Buffalo | Denver | 3 | -320 | |
| Detroit | -7 | New Orleans | New Orleans | 14 | -280 | 52 |
| Kansas City | -4 | Miami | Miami | 9 | -200 | 43 |
| Minnesota | 3 | Atlanta | Minnesota | 1 | -170 | 45 |
| N.Y. Giants | 3 | Carolina | Carolina | 1 | +155 | 46 |
| New England | 8 | Arizona | New England | 1 | -360 | 50 |
| Oakland | -7.5 | Houston | Houston | 4 | -320 | 45 |
| Seattle | -5.5 | N.Y. Jets | N.Y. Jets | 9 | -210 | 47 |
| St. Louis | -5.5 | San Francisco | San Francisco | 14 | -240 | 45 |
| Tampa Bay | 3 | San Diego | San Diego | 4 | +160 | 44 |
| Tennessee | 1 | Pittsburgh | Pittsburgh | 3 | -135 | 37 |
| Washington | -4.5 | Philadelphia | Philadelphia | 9 | -210 | 41 |
| Chicago | 6 | Green Bay | Chicago | 3 | -200 | 47 |
Talking points for Week 16
It's that time of year again, who cares if they win and will they show up. Carolina has been on a roll the last 3 weeks and looks to clinch the NFC South. San Diego is in a
must win situation in the sorry AFC West division. Other than the travel West to East, which has not been kind to West coast teams this year, the numbers still favor the Chargers.
| # of Bets | Amount Wagered | Payout | Profit |
| 3 | $300 | $540 | $240 |
**For comparison purposes, we picked $100 bets as our standard bet.